Comparing the Effect of Inhaler N-Acetyl Cysteine and Intravenous Dexamethasone on Respiratory Distress Syndrome in Premature Infants: A Randomized Clinical Trial

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Article Notes and Dates
To Cite : Najafian B, Khosravi M H, Setayesh F, Shohrati M. Comparing the Effect of Inhaler N-Acetyl Cysteine and Intravenous Dexamethasone on Respiratory Distress Syndrome in Premature Infants: A Randomized Clinical Trial, Thrita. 2017 ;6(1):e46268. doi: 10.5812/thrita.46268.
Copyright: Copyright © 2017, Thrita Journal. .
Abstract
1. Background
2. Methods
3. Results
4. Discussion
References
  • 1. Kliegman R, Behrman RE, Nelson WE. Nelson textbook of pediatrics. 2016;
  • 2. Najafian B, Karimi-Sari H, Khosravi MH, Nikjoo N, Amin S, Shohrati M. Comparison of efficacy and safety of two available natural surfactants in Iran, Curosurf and Survanta in treatment of neonatal respiratory distress syndrome: A randomized clinical trial. Contemp Clin Trials Commun. 2016; 3: 55-9[DOI]
  • 3. Soll R, Ozek E. Multiple versus single doses of exogenous surfactant for the prevention or treatment of neonatal respiratory distress syndrome. Cochrane Database Syst Rev. 2009; (1)[DOI][PubMed]
  • 4. Doyle LW, Ehrenkranz RA, Halliday HL. Dexamethasone treatment in the first week of life for preventing bronchopulmonary dysplasia in preterm infants: a systematic review. Neonatology. 2010; 98(3): 217-24[DOI][PubMed]
  • 5. Nayeri F, Movaghar-Nezhad K, Assar-Zadegan F. Effects of antenatal steroids on the incidence and severity of respiratory distress syndrome in an Iranian hospital. East Mediterr Health J. 2005; 11(4): 716-22[PubMed]
  • 6. Doyle LW, Ehrenkranz RA, Halliday HL. Early (< 8 days) postnatal corticosteroids for preventing chronic lung disease in preterm infants. Cochrane Database Syst Rev. 2014; (5)[DOI][PubMed]
  • 7. Papile LA, Tyson JE, Stoll BJ, Wright LL, Donovan EF, Bauer CR, et al. A multicenter trial of two dexamethasone regimens in ventilator-dependent premature infants. N Engl J Med. 1998; 338(16): 1112-8[DOI][PubMed]
  • 8. Halliday HL, Ehrenkranz RA, Doyle LW. Delayed (>3 weeks) postnatal corticosteroids for chronic lung disease in preterm infants. Cochrane Database Syst Rev. 2003; (1)[DOI][PubMed]
  • 9. Halliday HL, Ehrenkranz RA, Doyle LW. Moderately early (7-14 days) postnatal corticosteroids for preventing chronic lung disease in preterm infants. Cochrane Database Syst Rev. 2003; (1)[DOI][PubMed]
  • 10. Naz F, Raza AB, Ijaz I, Kazi MY. Effectiveness of nebulized N-acetylcysteine solution in children with acute bronchiolitis. J Coll Physicians Surg Pak. 2014; 24(6): 408-11[PubMed]
  • 11. Speer CP. Chorioamnionitis, postnatal factors and proinflammatory response in the pathogenetic sequence of bronchopulmonary dysplasia. Neonatology. 2009; 95(4): 353-61[DOI][PubMed]
  • 12. Mosca F, Mercadante D, Fumagalli M, Agosti M, Colnaghi M. Prevention and treatment of chronic lung disease. J Pediatr Neonat Individual Med. 2013; 2(2): 20212
  • 13. Halliday HL, Ehrenkranz RA, Doyle LW. Early postnatal (<96 hours) corticosteroids for preventing chronic lung disease in preterm infants. Cochrane Database Syst Rev. 2003; (1)[DOI][PubMed]
  • 14. Oktaviani F. Betamethasone was more effective than N-acetylcysteine for lung maturation. Indonesian J Obstet Gynecol. 2016; 37(1)
  • 15. Shah SS, Ohlsson A, Halliday HL, Shah VS. Inhaled versus systemic corticosteroids for the treatment of chronic lung disease in ventilated very low birth weight preterm infants. Cochrane Database Syst Rev. 2012; (5)[DOI][PubMed]
  • 16. Rao S, Wilson DB, Brooks RC, Sproule BJ. Acute effects of nebulization of N-acetylcysteine on pulmonary mechanics and gas exchange. Am Rev Respir Dis. 1970; 102(1): 17-22[DOI][PubMed]
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