Comparison of MicroRNAs Between Hepatocytes and Peripheral Blood Mononuclear Cells Involved in Hepatitis C Virus Infection

Authors Information
Article Notes and Dates
To Cite : Miri S M, Sharafi H, Karimi Elizee P, Alavian S M. Comparison of MicroRNAs Between Hepatocytes and Peripheral Blood Mononuclear Cells Involved in Hepatitis C Virus Infection, Thrita. 2017 ;6(1):e46666. doi: 10.5812/thrita.46666.
Copyright: Copyright © 2017, Thrita Journal. .
1. Context
2. Methods
3. Discussion
  • 1. Hadinedoushan H, Salmanroghani H, Amirbaigy MK, Akhondi-Meybodi M. Hepatitis C virus genotypes and association with viral load in yazd, central province of iran. Hepat Mon. 2014; 14(3)[DOI][PubMed]
  • 2. Taherkhani R, Farshadpour F. Epidemiology of hepatitis C virus in Iran. World J Gastroenterol. 2015; 21(38): 10790-810[DOI][PubMed]
  • 3. Zamani F, Sohrabi M, Poustchi H, Keyvani H, Saeedian FS, Ajdarkosh H, et al. Prevalence and risk factors of hepatitis C virus infection in amol city, north of iran: a population-based study (2008-2011). Hepat Mon. 2013; 13(12)[DOI][PubMed]
  • 4. Hsi E, Huang CF, Dai CY, Juo SH, Chou WW, Huang JF, et al. Peripheral blood mononuclear cells microRNA predicts treatment outcome of hepatitis C virus genotype 1 infection. Antiviral Res. 2014; 105: 135-42[DOI][PubMed]
  • 5. Bagaglio S, Uberti-Foppa C, Di Serio C, Trentini F, Andolina A, Hasson H, et al. Dynamic of Mixed HCV Infection in Plasma and PBMC of HIV/HCV Patients Under Treatment With Peg-IFN/Ribavirin. Medicine (Baltimore). 2015; 94(43)[DOI][PubMed]
  • 6. Coppola N, De Pascalis S, Pisaturo M, Paradiso L, Macera M, Capoluongo N, et al. Sustained virological response to antiviral treatment in chronic hepatitis C patients may be predictable by HCV-RNA clearance in peripheral blood mononuclear cells. J Clin Virol. 2013; 58(4): 748-50[DOI][PubMed]
  • 7. El-Awady MK, Abdel Rahman MM, Ismail SM, Amr KS, Omran M, Mohamed SA. Prediction of relapse after interferon therapy in hepatitis C virus-infected patients by the use of triple assay. J Gastroenterol Hepatol. 2003; 18(1): 68-73[DOI][PubMed]
  • 8. Hanno AFF, Mohiedeen KM, Alshayeb AF, Deghedy A. HCV RNA in peripheral blood mononuclear cells (PBMCs) as a predictor of the response to antiviral therapy in chronic hepatitis C. Alexandria Med J. 2014; 50(4): 317-22[DOI]
  • 9. Makvandi M, Khalafkhany D, Rasti M, Neisi N, Omidvarinia A, Mirghaed AT, et al. Detection of Hepatitis C virus RNA in peripheral blood mononuclear cells of patients with abnormal alanine transaminase in Ahvaz. Indian J Med Microbiol. 2014; 32(3): 251-5[DOI][PubMed]
  • 10. Zaman N, Asad MJ, Raza A, Raja GK, Akhter S, Mahmood M, et al. Presence of HCV RNA in peripheral blood mononuclear cells may predict patients response to interferon and ribavirin therapy. Ann Saudi Med. 2014; 34(5): 401-6[DOI][PubMed]
  • 11. Xu DZ, Xie Y, Li ZQ. Clearance of HCV RNA in peripheral blood mononuclear cell as a predictor of response to antiviral therapy in patients with chronic hepatitis C. Hepatobiliary Pancreat Dis Int. 2005; 4(4): 550-3[PubMed]
  • 12. Miri SM, Sharafi H, Salimi S, Bokharaei-Salim F, Behnava B, Keshvari M, et al. Assessment of HCV RNA in peripheral blood mononuclear cells as a predictor of response to Pegylated-interferon and Ribavirin: A cohort study. Iran Red Crescent Med J. 2017; [DOI]
  • 13. Miri SM, Sharafi H, Pouryasin A, Behnava B, Keshvari M, Salimi S, et al. The role of polymorphisms near IFNL3 gene as predictors of residual HCV RNA in buffy coat after successful antiviral therapy. Hepat Mon. 2017; 17(4)[DOI]
  • 14. Fognani E, Giannini C, Piluso A, Gragnani L, Monti M, Caini P, et al. Role of microRNA profile modifications in hepatitis C virus-related mixed cryoglobulinemia. PLoS One. 2013; 8(5)[DOI][PubMed]
  • 15. El-Guendy NM, Helwa R, El-Halawany MS, Abdel Rahman Ali S, Tantawy Aly M, Hasan Alieldin N, et al. The liver microrna expression profiles associated with chronic hepatitis C virus (HCV) genotype-4 infection: A preliminary study. Hepat Mon. 2016; 16(4)[DOI]
  • 16. Waldron PR, Holodniy M. MicroRNA and hepatitis C virus--challenges in investigation and translation: a review of the literature. Diagn Microbiol Infect Dis. 2014; 80(1): 1-12[DOI][PubMed]
  • 17. Omran AA, Osman KS, Kamel HM, Abdel-Naem EA, Hasan DE. MicroRNA-122 as a Novel Non-Invasive Marker of Liver Fibrosis in Hepatitis C Virus Patients. Clin Lab. 2016; 62(7): 1329-37[DOI][PubMed]
  • 18. Sidorkiewicz M, Grek M, Jozwiak B, Krol A, Piekarska A. The impact of chronic hepatitis C infection on cholesterol metabolism in PBMCs is associated with microRNA-146a expression. Eur J Clin Microbiol Infect Dis. 2017; 36(4): 697-702[DOI][PubMed]
  • 19. Grek M, Piekarska A, Bartkowiak J, Fendler W, Kuydowicz J, Wroblewski P, et al. Coordinated increase of miRNA-155 and miRNA-196b expression correlates with the detection of the antigenomic strand of hepatitis C virus in peripheral blood mononuclear cells. Int J Mol Med. 2011; 28(5): 875-80[DOI][PubMed]
  • 20. Gupta P, Liu B, Wu JQ, Soriano V, Vispo E, Carroll AP, et al. Genome-wide mRNA and miRNA analysis of peripheral blood mononuclear cells (PBMC) reveals different miRNAs regulating HIV/HCV co-infection. Virology. 2014; 450-451: 336-49[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiaion Alert via Google Reader

Cited By:

Thrita accepts terms & conditions of:

International Committee of Medical Journal Editors (ICMJE) Citedby Linking DOI enabled Crossref iThenticate COPE Cross Check