Thrita

Published by: Kowsar

The Effects of Origanum Majorana on Oxidative Stress and Histopathology of Renal Tissue among Streptozotocin-Induced Diabetic Rats

Mohammadhassan Ghosian Moghaddam 1 , Iman Ansari 2 , * , Mehrdad Roghani 3 and Mohammad Moradi 2
Authors Information
1 Biochemistry Department, Faculty of medicine, Shahed University, Tehran, IR Iran
2 Student Research Committee, Faculty of Medicine, Shahed University, Tehran, IR Iran
3 Physiology Department, Faculty of medicine, Shahed University, Tehran, IR Iran
Article information
  • Thrita: September 6, 2013, 2 (3); 29-34
  • Published Online: August 26, 2013
  • Article Type: Research Article
  • Received: November 26, 2012
  • Revised: January 9, 2013
  • Accepted: March 10, 2013
  • DOI: 10.5812/thrita.9282

To Cite: Ghosian Moghaddam M, Ansari I, Roghani M, Moradi M. The Effects of Origanum Majorana on Oxidative Stress and Histopathology of Renal Tissue among Streptozotocin-Induced Diabetic Rats, Thrita. 2013 ;2(3):29-34. doi: 10.5812/thrita.9282.

Abstract
Copyright © 2013, Thrita. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
Acknowledgements
Footnotes
References
  • 1. Wandell PE. Quality of life of patients with diabetes mellitus. An overview of research in primary health care in the Nordic countries. Scand J Prim Health Care. 2005; 23(2): 68-74[DOI][PubMed]
  • 2. Tripathi BK, Srivastava AK. Diabetes mellitus: complications and therapeutics. Med Sci Monit. 2006; 12(7)-47[PubMed]
  • 3. Suji G, Sivakami S. Approaches to the treatement of diabetes mellitus: an overview. Cell Mol Biol (Noisy-le-grand). 2003; 49(4): 635-9[PubMed]
  • 4. Shapiro K, Gong WC. Natural products used for diabetes. J Am Pharm Assn. 2002; 42(2): 217-226
  • 5. Yokozawa T, Yamabe N, Cho EJ, Nakagawa T, Oowada S. A study on the effects to diabetic nephropathy of Hachimi-jio-gan in rats. Nephron Exp Nephrol. 2004; 97(2)-48[DOI][PubMed]
  • 6. Pitocco D, Zaccardi F, Di Stasio E, Romitelli F, Santini SA, Zuppi C, et al. Oxidative stress, nitric oxide, and diabetes. Rev Diabet Stud. 2010; 7(1): 15-25[DOI][PubMed]
  • 7. Descorbeth M, Anand-Srivastava MB. Role of oxidative stress in high-glucose- and diabetes-induced increased expression of Gq/11alpha proteins and associated signaling in vascular smooth muscle cells. Free Radic Biol Med. 2010; 49(9): 1395-405[DOI][PubMed]
  • 8. Chang YC, Chuang LM. The role of oxidative stress in the pathogenesis of type 2 diabetes: from molecular mechanism to clinical implication. Am J Transl Res. 2010; 2(3): 316-31[PubMed]
  • 9. Pazdro R, Burgess JR. The role of vitamin E and oxidative stress in diabetes complications. Mech Ageing Dev. 2010; 131(4): 276-86[DOI][PubMed]
  • 10. Baig MA, Gawali VB, Patil RR, Naik SR. Protective effect of herbomineral formulation (Dolabi) on early diabetic nephropathy in streptozotocin-induced diabetic rats. J Nat Med. 2012; 66(3): 500-9[DOI][PubMed]
  • 11. Corcoran MP, Lamon-Fava S, Fielding RA. Skeletal muscle lipid deposition and insulin resistance: effect of dietary fatty acids and exercise. Am J Clin Nutr. 2007; 85(3): 662-77[PubMed]
  • 12. Lemhadri A, Zeggwagh NA, Maghrani M, Jouad H, Eddouks M. Anti-hyperglycaemic activity of the aqueous extract of Origanum vulgare growing wild in Tafilalet region. J Ethnopharmacol. 2004; 92(2-3): 251-6[DOI][PubMed]
  • 13. Lermioglu F, Bagci S, Onderoglu S, Ortac R, Tugrul L. Evaluation of the long-term effects of oleum origani on the toxicity induced by administration of streptozotocin in rats. J Pharm Pharmacol. 1997; 49(11): 1157-61[PubMed]
  • 14. Srihari T, Sengottuvelan M, Nalini N. Dose-dependent effect of oregano (Origanum vulgare L.) on lipid peroxidation and antioxidant status in 1,2-dimethylhydrazine-induced rat colon carcinogenesis. J Pharm Pharmacol. 2008; 60(6): 787-94[DOI][PubMed]
  • 15. Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes estimates for the year 2000 and projections for 2030. Diabetes care. 2004; 27(5): 1047-1053
  • 16. Bergeron R, Yao J, Woods JW, Zycband EI, Liu C, Li Z, et al. Peroxisome proliferator-activated receptor (PPAR)-α agonism prevents the onset of type 2 diabetes in Zucker diabetic fatty rats: a comparison with PPARγ agonism. Endocrinology. 2006; 147(9): 4252-4262
  • 17. Bagheri M, Joghataei MT, Mohseni S, Roghani M. Genistein ameliorates learning and memory deficits in amyloid beta(1-40) rat model of Alzheimer's disease. Neurobiol Learn Mem. 2011; 95(3): 270-6[DOI][PubMed]
  • 18. Tesch GH, Allen TJ. Rodent models of streptozotocin-induced diabetic nephropathy. Nephrology (Carlton). 2007; 12(3): 261-6[DOI][PubMed]
  • 19. Chtourou Y, Fetoui H, Sefi M, Trabelsi K, Barkallah M, Boudawara T, et al. Silymarin, a natural antioxidant, protects cerebral cortex against manganese-induced neurotoxicity in adult rats. Biometals. 2010; 23(6): 985-96[DOI][PubMed]
  • 20. Akiyama S, Katsumata S, Suzuki K, Nakaya Y, Ishimi Y, Uehara M. Hypoglycemic and hypolipidemic effects of hesperidin and cyclodextrin-clathrated hesperetin in Goto-Kakizaki rats with type 2 diabetes. Biosci Biotechnol Biochem. 2009; 73(12): 2779-82[PubMed]
  • 21. Folli F, Corradi D, Fanti P, Davalli A, Paez A, Giaccari A, et al. The role of oxidative stress in the pathogenesis of type 2 diabetes mellitus micro- and macrovascular complications: avenues for a mechanistic-based therapeutic approach. Curr Diabetes Rev. 2011; 7(5): 313-24[PubMed]
  • 22. Nwosu BU, Stavre ZG, Maranda L, Cullen K, Lee MM. Hepatic dysfunction is associated with vitamin D deficiency and poor glycemic control in diabetes mellitus. J Pediatr Endocrinol Metab. 2012; 25(1-2): 181-6[PubMed]
  • 23. Abascal K, Yarnell E. The many faces of silybum marianum (Milk Thistle): Part 1-Treating cancer and hyperlipidemia and restoring kidney function. Alternative Complementary Therapies. 2003; 9(4): 170-175
  • 24. Soto C, Recoba R, Barrón H, Alvarez C, Favari L. Silymarin increases antioxidant enzymes in alloxan-induced diabetes in rat pancreas. Comp Biochem Physiol. 2003; 136(3): 205-212
  • 25. Toklu HZ, Tunali-Akbay T, Erkanli G, Yuksel M, Ercan F, Sener G. Silymarin, the antioxidant component of Silybum marianum, protects against burn-induced oxidative skin injury. Burns. 2007; 33(7): 908-16[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:

Author(s):

Article(s):

Create Citiation Alert
via Google Reader

Readers' Comments